Tuesday, December 15, 2009

FREM2 Polymorphisms as Predictors of Alzheimer’s Disease Risk

Rutgers Inventor:
Derek Gordon, Ph.D.
Department of Genetics

Rutgers Technology #: 09-029

Invention Summary: Investigators at Rutgers have identified novel polymorphisms in the FREM2 gene that are associated with an unfavorable prognosis for Alzheimer’s in humans. This technology will allow the construction of transgenic animal models to study Alzheimer’s disease in vivo and help identify potential drugs against it.

Market Applications: Animal models, Alzheimer’s, Therapeutics, Phophylactics, Drug Discovery, Transgenesis.

Advantages: Novel assay for Alzheimer’s prognosis/diagnosis, ease of transgenesis, drug screen potential.

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